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Appetite hormones also affect hunger, cravings, fullness and consistency with eating habits

doi:10.1002/osp4.732

Key practice-changing messages: Obesity is recognised as a primary disease driver, not simply a risk factor

In terms of safety, TRT has its own considerations (polycythemia, prostate effects, etc.) which are unrelated to PT-141s profile

This allows researchers to test a range of doses on a smaller cohort, identifying the minimum effective dose and any potential adverse effects before committing to a larger, more resource-intensive study