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4,26 PLP deficiency has also been reported to be caused by displacement of pyridoxal phosphate from circulating albumin by acetaldehyde (an alcohol metabolite), which increases urinary excretion
Morton J, McLaughlin DM, Whiting S, Russell GF
That is where functional medicine tends to click for a lot of people
For competitive athletes, use could result in suspension or disqualification if detected in a doping control
These areas often do not respond well to medication, diet, or exercise
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