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New method for assessment of serum catalase activity

In the SUSTAIN 6 CVOT of subcutaneous semaglutide, an increase in diabetic retinopathy complications was seen in the semaglutide arm compared with placebo, although most of these patients had diabetic retinopathy at baseline [Citation8]

Neurobiol Stress 14:100326 Efstathiou V, Stefanou MI, Demetriou M, Siafakas N, Makris M, Tsivgoulis G, Zoumpourlis V, Kympouropoulos SP, Tsoporis JN, Spandidos DA, Smyrnis N, Rizos E (2022) Long covid and neuropsychiatric manifestations (review)

10.1038/nchembio779 39 MustafaA

Launching oral GLP-1s requires more than extending injectable playbooks

Yet in those with prediabetes, that signaling is impaired and glucagon stays inappropriately high, meaning the see-saw isnt working as intended