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The safest stacks are boring: GLP-1 agonists like Survodutide or Mazdutide, growth hormone secretagogues like GHRP 2 or Hexarelin, and peripheral metabolics like AOD-9604
B12 also plays a role in maintaining your nerve cells, helping them work properly and keeping your brain sharp
Is there any downtime or side effects
However, observational studies suggest that whilst acute toxicity remains exceptionally rare, sustained very high levels of B12particularly from supplements or injectionsmay be associated with certain health concerns, though these are correlations rather than proven causal relationships
Since many of my patients have MTHFR mutations ( gene mutations that make it more difficult for the body to convert cyanocobalamin into an active form of B12 ), I prefer to avoid this type of B12 supplementation
When arginate is clearly superior For oral administration, the arginate form is the clear winner
