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N Engl J Med 378(25):e34

doi:10.11124/jbisrir-2015-1987 [3] Piantanida E, Ippolito S, Gallo D, et al

Figure 2 The core characteristics and mechanisms of candidalysin are well-defined: it exerts cytotoxicity by membrane insertion/lytication, activates pathways such as EGFR-MAPK and NLRP3 inflammasome to induce inflammation and damage in host cells, and targeted anti-infection strategies against this toxin have been summarized (Lortal et al., 2025)

Phase 2 MARITIME data showed 20.0% body weight reduction at 420mg monthly dose over 52 weeks , matching weekly semaglutide and tirzepatide efficacy from a once-monthly format

Headaches Often due to: Dehydration Reduced food intake Electrolyte imbalance Less Common but Important Side Effects Acid reflux Dizziness Injection site irritation These are usually mild but should not be ignored if persistent

L-carnitine L-tartrate is another common form