there is an extremely small chance of reaction
PubMed Central , Chemical Research in Toxicology , vol
17 The exact chemical in these supplements that causes liver injury has not yet been determined
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Milk Thistle Side Effects And Safety Common Side Effects Milk thistle appears to be well-tolerated but can cause mild digestive symptoms, such as: Bloating, fullness, gas, or stomach pain Heartburn Nausea Changes in bowel habits Diarrhea Rare Side Effects Stop taking milk thistle and seek emergency medical care if you develop signs and symptoms of allergic reactions: Skin reactions (rash, hives, itching, eczema) Severe allergic reaction (anaphylaxis), including throat tightening, swelling, and difficulty breathing Warning: The risk of an allergic reaction to milk thistle is higher in people who are allergic to related plants such as ragweed, marigold, daisy, and chrysanthemum
It is likely that such antibodies affect only a small percentage of patients with schizophrenia (probably no more than 1% to 2%)