Pyruvate kinase M2 promotes de novo serine synthesis to sustain mTORC1 activity and cell proliferation
(PubMed) Schoenmakers E, Agostini M, Mitchell C, et al
Research has explored its interactions with extracellular matrix remodeling, collagen synthesis pathways, and cellular defense mechanisms linked to tissue maintenance and regeneration
However, critical gaps persist between research achievements and practical deployment
Another study found that for women undergoing IVF, higher levels of glutathione in a womans follicle translated into increased fertilization rates (Tola et al., 2013)
The gene expression data is particularly compelling