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The clinical case for combining AOD-9604 with GLP-1 therapy in patients who have plateaued is mechanistically coherent (the two compounds act on different sides of the energy balance equation through non-overlapping mechanisms) and is not supported by randomized controlled trial evidence for the specific combination
The efficacy of lipoic acid, administered either intravenously or orally, in the management of neuropathic symptoms has been examined in patients with diabetes
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