Future work must prioritize standardized wound models incorporating non-responsive controls to validate scaffold performance under clinically relevant conditions
Not conducted by MedTech Research Group
As long as cellular glutathione is above a level considered to be adequate, which is called homeostasis, GCL is inhibited from making gamma-glutamylcysteine (GGC), no matter how much cysteine is available
Glutathione is a small protein made of three amino acids: glycine, glutamate, and cysteine
Glutathione inside cells jumps into action, binding to these toxins and transforming them into less harmful compounds that can be safely eliminated (Ballatori et al., 2009)
This entire process is highly dependent on cellular energy, requiring adenosine triphosphate (ATP) to function correctly