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After reviewing literature and conducting a two-round Delphi survey with 42 experts, a consensus emerged that emphasizes prioritizing clinical symptoms in diagnosis, with serum B12 as a screening marker supported by methylmalonic acid or homocysteine levels for additional confirmation

Autoimmune and nerve support Chronic inflammation often plays a role in autoimmune diseases and nerve dysfunction

BDNF upregulation The most well-documented mechanism of Semax is its ability to upregulate brain-derived neurotrophic factor (BDNF) a protein that plays a central role in neurogenesis, synaptic plasticity, and the formation and maintenance of neural connections

[7] They are generally well-tolerated, with common adverse effects including headache, facial flushing, nasal congestion, and dyspepsia

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patients with certain metabolic disorders also exhibit marked increases in TMAO levels when supplemented with LC [26]