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FIGURE 4 This is complicated because as a polar, charged tripeptide, transport of GSH is significantly inhibited by the blood-brain barrier (BBB), thus limiting effective delivery to brain-resident immune cells such as microglia which are central drivers of neuroinflammatory pathology (Valdovinos-Flores and Gonsebatt, 2012

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Its interaction with opioid systems may also contribute to pain relief and further stress reduction, highlighting its potential therapeutic applications

HER-2/neu Suppression: Decreased oncogene expression and tumor burden in transgenic mice 4