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Approximately 15-20% of trial participants across both medications achieved what researchers term super-responder status, exceeding 30% weight loss

If nausea is manageable, stay the course

[63] They were examining hormones secreted during eating, and testing them on pig pancreases, leading to the discovery of GLP-1's significant effects in 1988

In individuals with obesity, reduction in body weight improves health status, including cardiometabolic risk

doi: 10.1016/S0140-6736(19)31149-3 14 GersteinHCColhounHMDagenaisGRDiazRLakshmananMPaisPet al