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Trx proteins undergo reversible protein-disulfide exchange reactions with their substrates [1,5]

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Nature 4 , 298306, doi:10.1038/nrd1695 (2005)

Squaric acid ester-based total synthesis of echinochrome A

It is a dipeptide, which is formed by amino acids such as methionine and lysine

Given that UFL1 predominantly localizes to the perinuclear ER 6,7 , we performed immunofluorescence staining and found that UFL1 and AKT1 mainly colocalized at the perinuclear region of MDA-MB-231 cells (Fig

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