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While the concept of post-inflammatory pigment deposition is biologically plausible in oral mucosa - the tissue does contain melanocytes capable of responding to inflammatory signals - the specific studies informing this article focus on other mechanisms: endocrine (Patil and Mitra 2026), medication-induced (Ajmera et al
Extrapolating from short-term obesity trial data to prolonged use in athletes is scientifically unjustifiable
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