According to the MHRA-approved SmPC, the most frequently reported side effects are gastrointestinal in nature and include: Nausea (very common, affecting more than 1 in 10 people) Diarrhoea (very common) Constipation (very common) Vomiting (very common) Abdominal pain (very common) Headache (very common) Fatigue (common, affecting up to 1 in 10 people) Dyspepsia (indigestion, common) These gastrointestinal effects typically occur during dose escalation and often improve as the body adjusts to the medication
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Ghosh-Swaby OR, Goodman SG, Leiter LA et al (2020) Glucose-lowering drugs or strategies, atherosclerotic cardiovascular events, and heart failure in people with or at risk of type 2 diabetes: an updated systematic review and meta-analysis of randomised cardiovascular outcome trials
It is intended to be used alongside a healthy diet and exercise to help improve blood sugar and help reduce cardiovascular risks
This leads to the activation of immune cells (e.g., T cells, B cells, NK cells, monocytes/macrophages) and dysfunction of glial cells, culminating in the release of pro-inflammatory cytokines and complement components such as C4
Just because our government approved these in small amounts as safe, these small amounts quickly add up