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Gastrointestinal Cytoprotection In its original gastric biology context, BPC-157 promotes mucosal integrity through prostaglandin-independent mechanisms, modulates enteric neuron and glial cell activity, counteracts NSAID-induced intestinal permeability, and demonstrates organoprotective activity across the alimentary canal from oesophagus to colon in a range of injury models including ethanol, aspirin, and restraint stress-induced lesions