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A patient suffering from severe, treatment-refractory hyperadrenergic POTSexperiencing debilitating tachycardia, tremors, and massive adrenaline surgeswas found to have a genetic polymorphism in their COMT pathway
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Genome wide association studies identified an increasing number of common variants associated with these diseases
Sex-specific associations with CAD, ischemic stroke, heart failure, and AF were obtained using logistic regression controlling for age, assay array, and 20 principal components
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