Geilen CC, Wieder T, Orfanos CE
The authors synthesized evidence that HGF/c-Met signaling is essential for brain development, synaptic plasticity, and cognitive function, with disruption of this pathway associated with cognitive decline in aging and neurodegenerative diseases
Most vets start on the lower end and adjust based on response
Furthermore, urothelium from individuals with IC has demonstrated reduced cell proliferation and increased cell permeability (Fiehn and Kim, 2014)
Since growth hormone release is regulated by the hypothalamus and pituitary gland, any influence on these neural systems might indirectly affect GH secretion
Deficiency is a widespread phenomenon