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Specific compatibility considerations include confirmation of absence of reducing agents for disulphide-containing peptides, BSA carrier supplementation for recombinant proteins, and acetic acid acidification for hydrophobic peptides requiring low pH solubilisation
However, MMA levels can be elevated in those with thyroid and kidney conditions, which limits the tests specificity (9, 10)
People who are generally healthy and who regularly eat animal products may not need to supplement at all
Regular blood tests check if the current injection schedule keeps B12 levels right
The NICE Clinical Knowledge Summary for vitamin B12 deficiency outlines specific treatment schedules: for patients without neurological symptoms, hydroxocobalamin 1 mg intramuscularly three times a week for 2 weeks
