Causes, Consequences and Public Health Implications of Low B-Vitamin Status in Ageing. Nutrients 8, no
Neurologic symptoms may take longer, but many people notice energy/mood improvements within days to weeks once deficiency is corrected
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Despite its importance, B12 deficiency is remarkably common particularly among vegetarians, older adults, individuals with digestive conditions, and anyone whose body has difficulty absorbing this vitamin from food or oral supplements
Doctors watch how patients are doing and if their vitamin B12 levels are getting back to normal
The 2017 Neelakantan paper in Biochemistry characterised a fluorescent assay for direct real-time monitoring of NNMT enzymatic activity, providing the analytical foundation for inhibitor screening including 5-Amino-1MQ (PMID 28121423)