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Banks and colleagues injected DSIP and four analogues intravenously into dogs and measured DSIP-like material in cerebrospinal fluid sampled from the posterior fossa over 60 minutes

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For long-term success, they should be combined with: Nutrition counseling to support a sustainable dietary pattern Exercise and physical therapy to strengthen the back and core Behavioral coaching to build lasting habits Additionally, patients should avoid the temptation of using GLP-1 medications as a quick fix or without medical supervision