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Previously described cardiovascular effects of GLP-1 RAs are primarily indirect and include enhanced endothelial function and myocardial metabolism, natriuresis and anti-inflammatory and blood pressure-lowering effects

In some patients, gastrointestinal side effects can be severe enough to lead to treatment discontinuation

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A physiologically relevant dose of 50% Egg-phosphatidylcholine is sufficient in improving gut permeability while attenuating immune cell dysfunction induced by a high-fat diet in male wistar rats

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Efficacy and safety of LY3298176, a novel dual GIP and GLP-1 receptor agonist, in patients with type 2 diabetes: a randomised, placebo-controlled and active comparatorcontrolled phase 2 trial