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Furthermore, its tolerability profile, which includes weight gain, edema/fluid retention, fractures, and (rarely) bladder cancer in long-term use, could hinder its potential repositioning for depression [173]
anthropometric and clinical characteristics: index weight, BMI, BMI class (overweight, obesity class IIII), and comorbidities (see Online Resource for full list and definitions)
However, oxidative stress induces phosphorylation and downregulates IB, an apoptosis antagonist, but the activated NF-B promotes cell proliferation and produces cancers [55,56,57,58]
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When lifestyle changes and supplements are not enough, or when an underlying cause has been identified, medical and surgical options exist: Varicocele repair - Varicocelectomy, surgical repair of the varicocele, is one of the most evidence-backed low sperm motility treatments
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