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Some patients achieve acceptable glycaemic control or weight management benefits at lower doses that produce fewer side effects

Primary outcomes were SUDs, well-being spectrum, and mental health disorders, such as autism spectrum disorder (ASD), attention deficit/hyperactivity disorder [ADHD], posttraumatic stress disorder [PTSD], schizophrenia, bipolar disorder [BD], major depressive disorder [MDD], Tourettes syndrome, and anorexia nervosa

Recent studies, such as the Step 1 trial extension, provide evidence that upon withdrawal of semaglutide , patients might experience weight gain, hinting at the potential for a relapse into obesity

2000;54:S339