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These engineered cells express the human glucagon-like peptide-1 receptor (GLP-1R) and a CRE-binding protein (CREB)-inducible SEAP reporter gene

Peak appetite reduction occurs around week 12 when reaching maintenance dose

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DixonSJLembergKMLamprechtMRSkoutaRZaitsevEMGleasonCEet alFerroptosis: an iron-dependent form of nonapoptotic cell death