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Qualification is based on BMI and health history BMI 35+ qualifies automatically

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The rectal administration is also beneficial for patients who may have difficulty swallowing pills or for those who have gastrointestinal issues that could interfere with the absorption of oral medications

The medication is administered as a once-weekly subcutaneous injection , with doses gradually increased over 16-20 weeks to minimise gastrointestinal side effects

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Myelopathy Neurological impairment caused by compression of the spinal cord