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This contrasts with findings from Glp1r:mTmG mouse models, where 78% of -cells appear GLP1R-positive, suggesting that technical limitations or post-transcriptional regulation may explain the discrepancy (Gray et al., 2020)

Insulin resistance is the decreased ability to respond to the effects of insulin

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IGF-I stimulates muscle growth by suppressing protein breakdown and expression of atrophy-related ubiquitin ligases, atrogin-1 and MuRF1

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