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Certain supplements may also support the body during the metabolic changes that accompany GLP-1 treatment
Patients on tirzepatide lost an average of 20.2% of their body weight over 72 weeks Patients on semaglutide lost an average of 13.7% of their body weight over the same period 47% more tirzepatide patients achieved 25% or greater body weight loss compared to semaglutide Tirzepatide also produced greater reductions in waist circumference across all dose comparisons A 2024 meta-analysis published in JAMA Internal Medicine analyzing real-world data from over 140,000 patients confirmed the same pattern: tirzepatide produced an average of 4.23 kg more weight loss than semaglutide across all doses and durations studied
If approved, orforglipron would be the first oral medication that directly competes with injectable GLP-1 therapies on efficacy
Reinforce that a certain amount of weight gain is necessary and expected
If you are pregnant, nursing, taking medication, or have a medical condition, consult your physician before making any lifestyle change, including trying a new product or food
Menstrual cycle regularity and improvement in insulin sensitivity can become noticeable in three months
