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However, its primary use is for managing Type 2 diabetes
Microbiol Mol Biol Rev (2002) 66:57991.10.1128/MMBR.66.4.579-591.2002 169 InokiKZhuTGuanKL
Exposing these patients to a medication with even theoretical C-cell proliferative potential is considered unacceptable risk
27 A recent phase II study of cilofexor given at doses of 30/day and 100 mg/day compared with placebo in 140 noncirrhotic NASH patients for 24 weeks showed a significant reduction in hepatic steatosis measured by magnetic resonance imaging-proton density fat fraction and a reduction in serum gamma-glutamyltransferase
Carnovale C, Perrotta C, Baldelli S, Cattaneo D, Montrasio C, Barbieri SS, Pompilio G, Vantaggiato C, Clementi E, Pozzi M (2023) Antihypertensive drugs and brain function: mechanisms underlying therapeutically beneficial and harmful neuropsychiatric effects