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GLP-1 agonists have been hailed as miracle drugs
ASCVD is the leading cause of morbidity and mortality in people with T2D [2, 3]
Oral semaglutide drugs like Ozempic also show promise as a weight-loss drug for people with obesity
With more than 1 billion people globally living with obesity, the addressable patient population is enormous
In a 3-week study in DIO mice, semaglutide dose-dependently reduced BW and suppressed food intake
A pharmacokinetic analysis of Retatrutide published in the Journal of Clinical Pharmacology reported a mean terminal half-life of approximately 6 days with a coefficient of variation below 30%, supporting reliable weekly dosing in primate models
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