The risk of developing these severe side effects is very small, but it is important that patients and healthcare professionals are aware and alert to the associated symptoms
The most common ones are vomiting, bloating, fatigue, headaches, nausea, constipation, and abdominal discomfort
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Phase II trials indicated significant weight loss and improved metabolic markers, underscoring the drugs potential
doi: 10.1155/2015/568408 167 KoderaRShikataKKataokaHUTakatsukaTMiyamotoSSasakiMet al
Discussion In this mechanistic analysis of the SUMMIT trial, we found that, compared with placebo, treatment with the long-acting glucose-dependent insulinotropic polypeptide receptor and glucagon-like peptide-1 receptor agonist tirzepatide reduced BP and estimates of circulatory volume expansion in patients with obesity-related HFpEF