Some patients shift timing seasonally or when work schedules change
Foods to prioritise include: Lean proteins: Chicken, turkey, fish, eggs, legumes, and low-fat dairy help preserve muscle mass and promote satiety Non-starchy vegetables: Leafy greens, broccoli, peppers, courgettes, and cauliflower provide volume and nutrients with minimal calories Whole grains: Oats, brown rice, quinoa, and wholemeal bread offer sustained energy and fibre Healthy fats in moderation: Avocados, nuts, seeds, and olive oil support nutrient absorption and hormone production Fruits: Including bananas, berries, apples, and citrus fruits for vitamins, minerals, and fibre Adequate fluids: Water, herbal teas, and sugar-free beverages to maintain hydration Foods that may worsen side effects or hinder progress: High-fat, greasy foods: Fried items, heavy cream sauces, and fatty meats can exacerbate nausea and delayed gastric emptying Ultra-processed foods: Crisps, biscuits, and ready meals often provide excess calories with poor nutritional value Sugary beverages: Soft drinks, fruit juices, and sweetened coffees add calories without promoting fullness Large portion sizes: Even healthy foods can impede weight loss if consumed in excessive quantities Alcohol: Provides empty calories and may increase appetite whilst lowering inhibitions around food choices During the initial titration period, smaller, lower-fat meals may be better tolerated as your body adjusts to the medication
Cons: only delivers B12, no hydration, no other vitamins, no add-ons
Reconstituted retatrutide is generally stable for 2-4 weeks when properly refrigerated
Nasal spray protocol: Dose: 200-500 mcg per application Frequency: 1 to 2 times daily Duration: 4 to 8 weeks Nasal delivery is particularly interesting for researchers focused on neurological applications, as the nasal route provides a potential pathway to bypass the blood-brain barrier through the olfactory and trigeminal nerve pathways
This is why we use a process called titration
