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"People with heart disease or high heart disease risk are more likely to remain alive, keep their kidney function, and stay off dialysis if they are treated with semaglutide." So, how does a drug developed to help people with type 2 diabetes and popularised as a weight-loss therapy help slow the progression of kidney disease

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In one study, testing with vasopressin unmasked a urinary concentration defect in ~20% of the participants ( Glomerular disease in pSS primarily takes the form of membranoproliferative glomerulonephritis (MPGN) and was observed in a substantial minority of patients in several bioptic studies ( Patients who suffer from renal complications of Sjogren's disease are treated with corticosteroids, immunosuppressants, or a combination of both

This change helps it keep working for a longer time, which means it can keep talking to the body's cells in a consistent way