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Important safety considerations include the risk of hypoglycaemia when used with insulin or sulfonylureas, potential interactions with oral contraceptives (requiring non-oral contraception or additional barrier methods for 4 weeks after initiation and each dose increase), risk of pancreatitis, gallbladder disease, and dehydration potentially leading to acute kidney injury

The article directs readers to the specific figures their pharmacy prints on the label

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Likewise, the elderly and people with certain gastrointestinal disorders may also have difficulty absorbing the vitamin

Month three often marks a turning point where the medications full effects become apparent, with some studies showing weight loss reaching 8-10% of starting body weight 2

References Belluz J