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Venous blood gas assessment confirmed severe metabolic acidosis, with pH 7.066, pCO 2 10.1 mmHg, HCO 3 7 mmol/l, BE -26,1 mmol/l.Capillary ketones (beta-hydroxy butyrate) were 5.1 mmol/l, urinalysis revealed ketonuria and glucosuria

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MT1 is applied as a selective MC1R agonist across several intersecting preclinical research domains

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Liver-derived acylcarnitine can be used as a signal molecule for inter-tissue communication to coordinate energy metabolism, highlighting the role of the liver as a metabolic center, and unveiling the new insight of the liver-organ axis