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Le diagnostic consiste gnralement mesurer les niveaux sriques de vitamine B12 ou identifier des niveaux levs d'acide mthylmalonique et d'homocystine

Calcification can be observed on MRI scans, particularly in patients who have experienced a stroke or traumatic brain injury, and this calcification may be related to the deterioration of melatonin synthesis, which decreases dramatically with age, potentially leading to issues such as precocious puberty in some cases 10s

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Occasional nausea has been reported, especially when taking the compound without food

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