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A total of 426 patients with peripheral sensory or motor neuropathy were included and treated with intramuscular acetyl-l-carnitine at a dose of 500 mg/twice daily for 10 days followed by 2 g/day for 20 days or placebo

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Antioxidant systems like SOD and glutathione peroxidase (GPx) reduce OH generation by scavenging O 2 and HO, thereby lowering oxidative stress and inhibiting pyroptosis [232]