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16.2 Immediate Management and Supportive Care Management is primarily supportive

The main symptoms include: Physical fatigue : a constant feeling of exhaustion that does not go away even after adequate rest or sleep

Routine monitoring of serum calcitonin or using thyroid ultrasound is of uncertain value for early detection of MTC in patients treated with RYBELSUS or OZEMPIC tablets [see Contraindications (4), Warnings and Precautions (5.1)]