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Furthermore, semaglutide (Table 1) shows distinct microbial profiles, featuring Akkermansia, Faecalibaculum, and Allobaculum, along with improved glucose tolerance and enhanced gut barrier integrity [46,47]
Food, environment, lifestyle and gut function may all influence gene expression, inflammation, mitochondrial function and methylation without changing the DNA sequence
Patients who use it to support structured protocols consistently outperform those relying on dietary restriction alone
Side effects such as nausea or stomach upset are common at first but usually decrease over time
Open communication with healthcare professionals and ongoing monitoring may help ensure that both physical and psychological needs are addressed throughout the course of GLP-1 therapy