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These ongoing protein dynamics are highly complex, with several allosteric inhibitors potentially able to act at a large distance from the core catalytic domains and to inhibit the enzymatic activity in cooperation with a variety of cofactors 2,7
A number of protein hormones are synthesized only by cells of the trophoblast lineage or in small quantities by other cell types, particularly neoplastic cells.11, 12 The genetic elements that determine the trophoblast-specific pattern of expression of these genes have yet to be fully elucidated
Shklar G, Schwartz J, Trickler D, Cheverie SR
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