Both groups received the maximum tolerated dose of their medication: Tirzepatide group: 10 mg or 15 mg weekly (Zepbound) Semaglutide group: 1.7 mg or 2.4 mg weekly (Wegovy) Participants had a BMI of 30 or higher, or a BMI of 27 or higher with at least one weight-related health condition
However, in the SURMOUNT 3 trial involving adults without T2D, tirzepatide-treated females were significantly more likely to achieve a body weight reduction of at least 5% and 10% than tirzepatide-treated males
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Some patients have lost up to 10-15% of their baseline weight within three to six months of starting weight loss injectable therapy
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doi: 10.1016/j.jpainsymman.2006.09.001 35 HolckAWolkowitzOMellonSReusVNelsonJWestrinet al