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Niedwied A et al
While they are normally the result of stress, various environmental factors such as smoke and pollutants can also trigger their formation
Kato S, Fukui K, Kirigaya H, Gyotoku D, Iinuma N, Kusakawa Y, Iguchi K, Nakachi T, Iwasawa T, Kimura K (2016) Inhibition of DPP-4 by alogliptin improves coronary flow reserve and left ventricular systolic function evaluated by phase contrast cine magnetic resonance imaging in patients with type 2 diabetes and coronary artery disease
Hypertrophy + hyperplasia Animal-model research shows IGF-1 LR3 drives both fibre growth (hypertrophy) and new fibre formation (hyperplasia) - distinct from most anabolic agents
But stress, medications, aging, and bad health can deplete glutathione levels
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