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Patients were screened to include only those who were GLP-1RA-nave, defined as having no recorded GLP-1RA purchases during the 365-day pre-index period, in the final analytical dataset

Key risks include worsened gastrointestinal side effects (nausea, vomiting), hypoglycaemia (particularly in patients taking insulin or sulfonylureas), dehydration, inadequate nutritional intake, and potential exacerbation of pancreatitis or gallbladder problems

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Here Vitamin B12 combines a protein called intrinsic factor for its absorption into the small intestines

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Finding: 14% reduction in major adverse cardiovascular events (MACE) with oral semaglutide