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10.1016/j.psyneuen.2011.04.012 6 AsadiS.GholamiM

One study reported a composite outcome of mortality and hospitalisation for heart failure ( n =131,196) and found a reduced risk with combination therapy (HR 0.77 [95% CI 0.69, 0.86]) [26]

Nau The primary outcomes were rates of hypertensive disorders of pregnancy, gestational diabetes, preterm birth and cesarean delivery between the two cohorts

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Treatment decisions, medication selection, dosing, and eligibility are determined by a licensed clinician after review

31 , 32 Los estudios clnicos ya han demostrado que la adicin de iSGLT2 a los iDPP4 mejora las concentraciones de glucosa con prdida significativa de peso, 33 , 34 y al tener en cuenta que los pacientes con diabetes mellitus tipo 2 tienen de base aumento del glucagn y de la gluconeognesis heptica, 35 - 39 se ven beneficiados con la administracin de AGLP1