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Flick the syringe to get any air bubbles to the top and gently push them out

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It occurs exclusively in the cytosol, where glutamate cysteine ligase (GCL) and glutathione synthetase (GS) perform their function

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Phase (approx.) Cagrilintide dose Frequency Weeks 14 0.25 mg Once weekly Weeks 58 0.5 mg Once weekly Weeks 912 1.0 mg Once weekly Weeks 1316 1.7 mg Once weekly Week 17 onward 2.4 mg (max studied) Once weekly This step-wise schedule mirrors the titration used in cagrilintide and CagriSema studies ( Lau et al., Lancet 2021

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