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Furthermore, its protective effect in APAP-induced hepatotoxicity was linked to reduced mitochondrial dysfunction, oxygen consumption, and membrane potential (Lu et al., 2015
JB Lippincott Co, 1965-1983, 1993
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However, basal levels of phase I and most phase II drug metabolizing enzymes in HepG2 cells are very low compared to human hepatocytes ( GSTP1 gene
In anticipation of the antioxidant effect of NAC, clinical trials have been conducted on various neuropsychiatry diseases and neurodegenerative diseases 50,51,52
