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Side Effects Both forms share similar semaglutide side effects, primarily gastrointestinal symptoms including nausea (46.6%), vomiting (30.9%), and constipation (20.1%)
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[7] Both metformin and GLP-1RAs are known to improve leptin sensitivity, making the brain more responsive to the anorexigenic effects of the adipokine
M.et al (2014)