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5 Transgenerational effects of environmental endocrine disruptors on reproductive health Mounting evidence suggests that environmental endocrine disruptors impose reproductive health consequences that extend far beyond the directly exposed individual, manifesting as heritable dysfunction transmitted across multiple generations

individuals with this condition can fully absorb the free form (15)

PMID 16537422

For example, those with Crohns disease or after gastric bypass might not absorb Vitamin B12 well

Severe deficiency : Weekly or biweekly injections may initially be required to correct anemia and neurological symptoms

18 As Thakkar and Billa, they point out potential concerns for smokers, but again this is based on an article from 1970