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This was probably due to the fact that the modification inhibited the interaction between the peptides and cell surface membranes

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Epithalon also seemed to inhibit the activity of Caspase-3, a crucial enzyme believed to facilitate apoptosis (programmed cell death)

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l-dopa) can cross the BBB and reach brain tissue via l-type amino acid transporter-1 (LAT-1), the member of solute carrier (SLC) family present at the brain endothelium and diverse brain cells [6]

Instead, CHOP appears to act as a transcriptional decoy