Results vary, and a lower dose should not automatically be expected to produce steady or sustained weight loss
Buse JB, Klonoff DC, Nielsen LL et al (2007) Metabolic effects of two years of exenatide treatment on diabetes, obesity, and hepatic biomarkers in patients with type 2 diabetes: an interim analysis of data from the open-label, uncontrolled extension of three double-blind, placebo-controlled trials
While the exact mechanism isnt fully understood, it may relate to GLP-1s effects on fluid balance, autonomic nervous system regulation, or as a secondary consequence of other side effects like nausea or reduced fluid intake
Rats and rabbits were exposed to insulin glargine in animal reproduction studies during organogenesis, respectively 50 times and 10 times the human subcutaneous dosageof 0.2 units/kg/day
It can also improve mood and regulate appetite
The Connection to SI Joint Instability When the muscles around the pelvis weaken, the SI joint may become unstable